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Image Search Results
Journal: Cell reports
Article Title: Intestinal IL-17R Signaling Constrains IL-18-Driven Liver Inflammation by the Regulation of Microbiome-Derived Products
doi: 10.1016/j.celrep.2019.10.042
Figure Lengend Snippet: (A and B) Littermate Il17ra fl/fl and Il17ra fl/fl × villin cre + mice were either cohoused or separated for 1 week. Mice were then treated with concanavalin A (Con A) (25 mg/kg), and serum alanine aminotransferase (ALT) was measured at 8 h (n = 6–14 mice/group). (C) 16S sequencing on terminal ileum of littermate Il17ra fl/fl and Il17ra fl/fl × villin cre + mice at the naive state and 8 h post Con A (25 mg/kg) (n = 7–16 mice/group). (D and E) Mice were treated with either 5 days of 1 g/L neomycin (D) or 14 days of 0.5 g/L vancomycin (E) in the drinking water ad libitum . Mice were then injected with Con A and serum ALT was measured 8–9 h post injection. (n = 4– mice/group). (F) 16S rRNA transcript was measured by qRT-PCR in the liver of naive littermate Il17ra fl/fl and Il17ra fl/fl × villin cre + mice (n = 7–10 mice/group). (G and H) Liver homogenate (G) and serum (H) from naive littermate Il17ra fl/fl and Il17ra fl/fl × villin cre + mice were plated on mTLR9 SEAP reporter cells. Absorbance of supernatants represented as ratio over null/unstimulated cells. (n = 4–8 mice/group). (A, B, and D–H) Data are represented as mean + SEM. (unpaired t test; multiple t tests per row; Mann-Whitney test). p<0.05*, <0.01**, <0.001***, <0.0001**** See also .
Article Snippet: Mouse TLR9 and
Techniques: Sequencing, Injection, Quantitative RT-PCR, MANN-WHITNEY
Journal: Cell reports
Article Title: Intestinal IL-17R Signaling Constrains IL-18-Driven Liver Inflammation by the Regulation of Microbiome-Derived Products
doi: 10.1016/j.celrep.2019.10.042
Figure Lengend Snippet:
Article Snippet: Mouse TLR9 and
Techniques: Recombinant, Purification, Activity Assay, In Situ, Enzyme-linked Immunosorbent Assay, Bicinchoninic Acid Protein Assay, Staining, RNA Sequencing Assay, Sequencing, Software, SYBR Green Assay, Protease Inhibitor, Cell Counting